Cyclometallated platinum(IV) compounds as promising antitumour agents
نویسندگان
چکیده
منابع مشابه
Nitric oxide donor hybrid compounds as promising anticancer agents.
Nitric oxide (NO) plays important roles in cardiovascular regulation, nerve transmission delivery and immune responses. In the last semicenturry, it has been proved that though low concentration of NO is tumor-promoting, high concentration of NO could exhibit multiple antitumor effects, which led to the research and development of kinds of NO donors and NO donor hybrid compounds as antitumor ag...
متن کاملExploring the potential of gold ( III ) cyclometallated compounds as cytotoxic agents : variations on the
A series of novel (C^N) cyclometallated Au(III) complexes of general formula [Au(py-H)LL] (py-H = C^N cyclometallated 2-benzylpyridine, L and L being chlorido, phosphane or glucosethiolato ligands, n = 0 or 1) have been synthesized and fully characterized using different techniques, including NMR, IR and far-IR, mass spectrometry, as well as elemental analysis. The crystal structure of one comp...
متن کاملTowards the use of cannabinoids as antitumour agents
| Various reports have shown that cannabinoids (the active components of marijuana and their derivatives) can reduce tumour growth and progression in animal models of cancer, in addition to their well-known palliative effects on some cancer-associated symptoms. This Opinion article discusses our current understanding of cannabinoids as antitumour agents, focusing on recent insights into the mol...
متن کاملExploring the potential of gold(III) cyclometallated compounds as cytotoxic agents: variations on the C^N theme.
A series of novel (C^N) cyclometallated Au(III) complexes of general formula [Au(py(b)-H)L(1)L(2)](n+) (py(b)-H = C^N cyclometallated 2-benzylpyridine, L(1) and L(2) being chlorido, phosphane or glucosethiolato ligands, n = 0 or 1) have been synthesized and fully characterized using different techniques, including NMR, IR and far-IR, mass spectrometry, as well as elemental analysis. The crystal...
متن کاملSignal Transduction Inhibitors as Promising Anticancer Agents
1Laboratory for Drug Design and Synthesis, Centre for Chemical and Pharmaceutical Sciences, Central University of Punjab, Bathinda Punjab 151001, India 2Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, 720 BRB-II/III, 421 Curie Boulevard Philadelphia, PA 19104-6160, USA 3The Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Organometallic Chemistry
سال: 2019
ISSN: 0022-328X
DOI: 10.1016/j.jorganchem.2018.10.008